We offer a full range of irritation and allergy patch testing, including 24 to 96 hour irritation protocols, HRIPT protocols, allergy and photo allergy testing. With over 30 years’ experience in safety testing and our Dermatology heritage, we have huge experience in these types of tests. Choosing the wrong safety testing and then suffering consumer reactions to a product in the market can be hugely damaging to a brand reputation, so talk to the experts to ensure your products are tested effectively to minimize risks.
The most common types of test are:
- 24/48 Hour Patch Test.
- 96 hour Cumulative Irritancy Patch Test.
- 14 Day Cumulative Irritancy Patch Test/ Human Repeat Insult Patch Test (HRIPT).
Variations on these tests are available and all can be by occlusive or non occlusive application.
Some chemicals only become skin irritants (photo-irritants) or allergens (photo-allergens) after activation by Ultra violet (UV) light.
The test product is applied to the skin under occlusion for 24 or 48 hours. The test sites are irradiated with UVA followed by UVB and assessed subsequently for the development of photo-irritancy.
The test protocol mirrors the sensitization test and is as follows:
- A minimum of 50 subjects are needed for reliable information.
- Three weeks induction period with skin exposure under occlusion followed by UVB irradiation twice weekly.
- Rest phase of two weeks with no application.
- Photo – allergy (photo-sensitisation) challenge in sixth week using UVA and UVB.